In the read more early 2010s, the United states was struck from the “opioid crisis”, as illicit fentanyl and new synthetic opioids (NSOs) flooded the unlawful drug industry. Benzimidazole opioids are µ-opioid receptor (MOR) agonists with antinociceptive Qualities. Even though the potency of some of these compounds is similar to that of morphin